The differences in blood protein levels during childhood and early adulthood were recently explored in an article published in Nature Communications.

In this study Olink Explore HT was used to measure protein levels in blood samples from 100 participants in the population-based Swedish cohort BAMSE (Barn(Child), Allergy, Milieu, Stockholm, Epidemiology) at ages 4, 8, 16 and 24 years. The results showed that the levels of more than half of the measured proteins changed with age already during childhood and adolescence. Sex-specific patterns were also observed, particularly during and after puberty.

These findings highlight the importance of accounting for age and sex when analysing protein levels in children, both when studying normal development but also when focusing on different diseases and conditions. The results have also been published on the Human Protein Atlas as a part of the Human Disease Blood Atlas in the Blood resource.

Read the article

Check out the gene COL9A1 in the Atlas