The differences in blood protein levels during childhood and early adulthood were recently explored in an article published in Nature Communications...Read more

The Human Protein Atlas supports the global effort announced by Biohub to create an open data foundation for AI-accelerated biology. The initiative brings together leading institutions and international consortia to generate the technologies and multi-modal datasets needed to build predictive models of the human cell...Read more

The nucleus of mammalian cells is highly compartmentalized both in terms of DNA and protein organization. Speckles are large membrane-less irregularly shaped nuclear condensates with a dynamic composition of hundreds of different proteins, many of which are involved in RNA splicing. Evidence from recent studies points towards an interesting connection between the evolution of nuclear speckles and genome structure in terms of base composition, gene clustering and 3D-genome organization...Read more

In a review article published in Pharmacological reviews the current knowledge of molecular features, functions, and opportunities for therapeutic targeting of human and mammalian aGPCRs is summarised...Read more

In this edition of multiplex tissue image of the month, meiosis-associated BEN domain containing 2 (gene: BEND2) is showcased within developing spermatocytes in testis...Read more